FATORES ASSOCIADOS AO EXCESSO DE PESO EM CRIANÇAS COM TRANSTORNO DO ESPECTRO AUTISTA
Palavras-chave:
Sobrepeso, Transtorno Autístico, Ingestão de Alimentos, Nutrição da criançaResumo
Objetivo: Avaliar os fatores associados ao excesso de peso em crianças com Transtorno do Espectro Autistas – TEA. Métodos: Estudo transversal realizado com crianças autistas assistidas em instituições de apoio no município de Maceió, Alagoas, no ano de 2018. Dados clínicos e antropométricos, além de informações sobre o consumo alimentar, foram obtidos por aplicação de questionário padronizado. O teste de regressão de Poisson foi utilizado para avaliação dos fatores associados ao desfecho, com resultados expressos por Razão de prevalência (RP) e respectivos intervalos de confiança a 95% (IC 95%) considerando p< 0,05 como significativo. Resultados: A população do estudo foi composta por 84 crianças autistas. A escolaridade materna [RP=1,09; (1,01-1,18); p=0,02]; tipo de parto [RP=1,12; (1,04-1,20); p=0,001; número de refeições [RP=0,91; (0,86-0,96); p= 0,001; uso de antibióticos [RP=1,0; (0,99-1,02); p= 0,208; consumo de frutas [RP=0,92; (0,85-0,98); p= 0,02; consumo de embutidos [RP=0,91; (0,83-0,99); p= 0,04 foram associados ao excesso de peso. Conclusão: O presente estudo mostrou que o excesso de peso é um problema expressivo em crianças com TEA. A baixa escolaridade materna, o uso de antibióticos na gestação, o nascimento do tipo cesariano, configuraram-se como fator preditor do sobrepeso e obesidade, enquanto consumir mais refeições e consumir frutas parecem atuar como protetores no desencadeamento do evento aqui estudado.
Referências
American psychiatric association (apa). Diagnostic and statisticalmanual of mental disorders (DSM-5). thed. Washington, DC:American Psychiatric Association; 2013.
Christensen DL, Braun KVN, Baio J, et al. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network. MMWR Surveill Summ 2018; 65(2);1?23.
Zuckerman KE, Hill AP, Guion K, Voltolina L et al. Overweight and obesity: prevalence and correlates in a large clinical sample of children with autism spectrum disorder. J Autism Dev Disord 2014; 44 (7):1708?1719.
Phillips KL, Schieve LA, Visser S, et al. Prevalence and impact of unhealthy weight in a national sample of US adolescents with autism and other learning and behavioral disabilities. Matern Child Health J 2014; 18 (8):1964-1975.
MUST A, Curtin C, Hubbard K, et al. Obesity prevention for children with developmental disabilities. Curr Obes Rep 2014; 3 (2): 156-170.
Pan W, Kastin AJ. Adipokines and the blood-brain barrier. Peptides. 2007; 28 (6):1317?1330.
San Mauro-Martin I, Onrubia-Gonzalez-De La Aleja J, Garicano-Vilar E, et al. Analisis del estado nutricional y composicion corporal de personas con discapacidad intelectual [Analysis of the nutritional status and body composition of persons with intellectual disability]. Rev Neurol. 2016; 62 (11):493?501.
Centers for Disease Control and Prevention. Prevalence of autism spectrum disorder among children aged 8 years – autismo and developmental disabilities monitoring network. MMWR Surveill Summ 2016; 63 (6):1-21.
Chor D, Alves MGM, Giatti, L, et al. Questionário do ELSA-Brasil: desafios na elaboração de instrumento multidimensional. Rev Saúde Pública 2013; 47 (2):27-36.
Organização Mundial da Saúde (OMS). Indicators for assessing infant and young child feeding practices. Geneva: WHO; 2010.
Brasil. Ministério da Saúde. Sistema de Vigilância Alimentar e Nutricional (SISVAN): Orientações básicas para a coleta, processamento, análise de dados e informação em serviços de saúde. Brasília: Ministério da Saúde, 2004.
Boccolini CS, Carvalho ML, Oliveira MI, et al. Fatores associados ao aleitamento materno exclusivo nos primeiros seis meses de vida no Brasil: Revisão Sistemática. Revista de Saúde Pública 2015; 49: 1-16.
Curtin C, Jojic M, Bandini LG. Obesity in children with autism spectrum disorder. Harv Rev Psychiatry 2014; 22(2): 93?103.
Cortese S, Moreira-Maia CR, St Fleur D, et al. Association Between ADHD and Obesity: A Systematic Review and Meta-Analysis. Am J Psychiatry 2016; 173(1):34-43.
Kummer A, Barbosa IG, Rodrigues DH, et al. Frequência de sobrepeso e obesidade em crianças e adolescentes com autismo e transtorno do déficit de atenção / hiperatividade. Rev Paul Pediatr. 2016; 34(1): 71-77.
Caetano MV, Gurgel DC.Perfil nutricional de crianças portadoras do transtorno do espectro autista. Rev Bras em Promoç da Saúde 2018; 31(1):1-11.
Khalife N, Kantomaa M, Glover V, et al. Childhood attention-deficit/hyperactivity disorder symptoms are risk factors for obesity and physical inactivity in adolescence. J Am Acad Child Adolesc Psychiatry 2014; 53(4):425?436.
Silveira JA, Colugnati FA, Cocetti M, et al. Secular trends and factors associated with overweight among Brazilian preschool children. J Pediat 2014; 90(3): 258-66.
Charlotte Jansen, Eva Pajkrt. Authors' reply re: Vaginal delivery in women with a low?lying placenta: a systematic review and meta?analysis, BJOG: An International Journal of Obstetrics & Gynaecology 2019; 127(3): 429-430.
Liang J, Zhang Z, Yang W, et al. Association Between Cesarean Section and Weight Status in Chinese Children and Adolescents: A National Survey. Int J Environ Res Saúde Pública 2017; 14(12): 1609-1620.
Jakobsson HE, Abrahamsson TR, Jenmalm MC, et al. Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section. Gut 2014; 63(4):559-566.
Frazier TW, Shattuck PT, Narendorf SC, et al. Prevalence and correlates of psychotropic medication use in adolescents with an autism spectrum disorder with and without caregiver-reported attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol 2011; 21(6):571?579.
Malone RP, Cater J, Sheikh RM, Choudhury MS, Delaney MA. Olanzapine versus haloperidol in children with autistic disorder: an open pilot study. J Am Acad Child Adolesc Psychiatry 2001; 40(8):887-894.
Dhaliwal KK, Orsso CE, Richard C, et al. Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder. International Journal of Molecular Sciences 2019; 20(13):3285-4013.
Ajslev TA, Andersen CS, Gamborg M, et al. Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics. Int J Obes (Lond) 2011; 35(4):522-529.
Scott FI, Horton DB, Mamtani R, et al. Administration of Antibiotics to Children Before Age 2 Years Increases Risk for Childhood Obesity. Gastroenterology 2016; 151(1):120-129.
Shao X, Ding X, Wang B, et al. Antibiotic Exposure in Early Life Increases Risk of Childhood Obesity: A Systematic Review and Meta-Analysis. Front Endocrinol (Lausanne) 2017; 8:170-180.
Cermak SA, Curtin C, Bandini LG. Food selectivity and sensory sensitivity in children with autism spectrum disorders. J Am Diet Assoc 2010; 110(2): 238-246.
Chistol LT, Bandini LG, Must A, et al. Sensory Sensitivity and Food Selectivity in Children with Autism Spectrum Disorder. J Autism Dev Disord. 2018; 48(2):583?591.
Ambrosini GL, Emmett PM, Northstone K, et al. Identification of a dietary pattern prospectively associated with increased adiposity during childhood and adolescence. Int J Obes. 2012; 36(10):1299-1305.
Rauber F, Campagnolo PD, Hoffman DJ, Vitolo MR. Consumption of ultra-processed food products and its effects on children's lipid profiles: a longitudinal study. Nutr Metab Cardiovasc Dis 2015; 25(1):116-122.
Bezerra IN, Cavalcante JB, Moreira TMV, et al. Eating away from home and excess weight: an analysis of explanatory mechanisms Rev Bras Prom Saúde 2016; 29(3):455-461.
World Health Organization (WHO). Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation. Geneva: WHO; 2003.
Meguid NA, Anwar M, Bjorklund G, et al. Dietary adequacy of Egyptian children with autism spectrum disorder compared to healthy developing children. Metab Brain Dis 2017;32: 607-615.
Berding K, Donovan SM. Berding K, et al. Diet Can Impact Microbiota Composition in Children With Autism Spectrum Disorder. Front Neurosci 2018; 12: 515-530.
Hubbard KL, Anderson SE, Curtin C, et al. A comparison of food refusal related to the characteristics of food in children with autism spectrum disorder and children in typical development. Journal of the Academy of Nutrition and Dietetics 2014; 114 (12): 1981-1987.
Coulthard H, Blissett J. Fruit and vegetable consumption in children and their mothers. Moderating effects of child sensory sensitivity. Appetite 2009; 52(2): 410-415.
Lane, AE, Young, RL, Baker, AEZ, et al. Sensory processing subtypes in autism: association with adaptive behavior. J Autism Dev Disord 2010;40(1):112-122.
Chen, H., & Liu, R. H. Potential mechanisms of action of dietary phytochemicals for cancer prevention by targeting cellular signaling transduction pathways. Journal of Agricultural and Food Chemistry 2018; 66(13): 3260–3276.
Malhi P, Venkatesh L, Bharti B, et al. Feeding Problems and Nutrient Intake in Children with and without Autism: A Comparative Study. Indian J Pediatr 2017; 84(4):283?288.
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