APPLICATION OF NANOFAT ADJUVANT TO SKIN GRAFT

Authors

  • Adriano Calcagnotto Garcia
  • Guilherme Augusto Hettwer HSL-PUCRS
  • Ricardo Kunz Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS
  • Guilherme Pereira Smaniotto HSL-PUCRS
  • Lucas Pastori Steffen Lutheran University of Brazil image/svg+xml
  • Milton Paulo de Oliveira Hospital São Lucas/PUCRS

DOI:

https://doi.org/10.63845/35nfxc81

Keywords:

Nanofat, Microfat, Fat graft

Abstract

Fat transfer has evolved from simple grafting techniques injection of smaller samples (microfat) and stem cells derived from adipose tissue (nanofat). While microfat aims to create volume in tissues, nanofat has demonstrated a regenerative effect, dueto concentrations of adipose tissue-derived mesenchymal stem cells (AD-MSCs). Therefore, benefits are likely to be expected from using nanofat in restorative procedures such as skin grafting. A 48-year-old patient presented with foot injury that involved bilateral partial amputation. Subsequently, a skin graft using nanofat was indicated on right foot, with better revolution when compared to a graft on the left foot not treated with fat. New fat graft transfer techniques are likely to be good options for aesthetic and regenerative procedures. However, further research is need before expanding the use of these products the clinical setting.

 

696 412

Author Biographies

  • Adriano Calcagnotto Garcia

    Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS

  • Guilherme Augusto Hettwer, HSL-PUCRS

    Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS

  • Ricardo Kunz, Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS

    Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS

  • Guilherme Pereira Smaniotto, HSL-PUCRS

    Médico residente do serviço de Cirurgia Plástica do HSL-PUCRS

  • Lucas Pastori Steffen, Lutheran University of Brazil

    Estudante de Medicina da Universidade Luterana do Brasil

  • Milton Paulo de Oliveira, Hospital São Lucas/PUCRS

    Chefe do Serviço de Cirurgia Plástica do Hospital São Lucas/PUCRS

References

Pretto AS, Pretto L, Souza AFD, Chem EM, Ely PB, Bonamigo RR. Allogeneicskindonorsfrom a tissue bank in Southern Brazil: clinicalandepidemiological profiles and microbial colonizationofskin. Int J Dermatol. 2019 Mar;58(3):325-32. doi: 10.1111/ijd.14254. DOI: https://doi.org/10.1111/ijd.14254

Ribeiro SG, Zanatelli C, Schorer B, Chem EM. Banco de Tecidos Humanos - Relatório Descritivo do Segmento Pele. Porto Alegre (RS): Banco de Pele Dr. Roberto Corrêa Chem/ICSMPA. 2022.

Koob, T J., Rennert, R., Zabek, N., Massee, M., Lim, J. J., Temenoff, J. S., Gurtner, G. Biologicalpropertiesofdehydratedhumanamnion/chorioncompositegraft: implications for chronicwoundhealing. InternationalWoundJournal. 2013; 10(5), 493–500. doi:10.1111/iwj.12140. DOI: https://doi.org/10.1111/iwj.12140

Mohammadi AA, Johari HG, Eskandari S. Effectofamnioticmembraneongraft take in extremityburns. Burns. 2013;39(6):1137‐41. DOI: https://doi.org/10.1016/j.burns.2013.01.017

Mohammadi AA, Riazi H, Hasheminasab MJ, Sabet B, Mohammadi MK, Abbasi S, et al. Amnioticmembranedressingvsconventional topical antibioticdressing in hospitalizedburnpatients. IRCMJ 2009;11(1):66–70.

Branski LK, Herndon DN, Celis MM, Norbury WB, Masters OE, Jeschke MG. Amnion in thetreatmentofpediatricpartial-thickness facial burns. Burns. 2008;34:393–9. DOI: https://doi.org/10.1016/j.burns.2007.06.007

Kogan S, Sood A, Granick MS. AmnioticMembraneAdjunctsandClinicalApplications in WoundHealing: A Review oftheLiterature. Wounds. 2018 Jun;30(6):168-173.

Published

2022-04-28

How to Cite

1.
Calcagnotto Garcia A, Hettwer GA, Kunz R, Pereira Smaniotto G, Pastori Steffen L, de Oliveira MP. APPLICATION OF NANOFAT ADJUVANT TO SKIN GRAFT. Rev. Arq Catarin Med [Internet]. 2022 Apr. 28 [cited 2026 Sep. 21];51(1):08-12. Available from: https://revista.acm.org.br/arquivos/article/view/1175

Most read articles by the same author(s)

Similar Articles

1-10 of 18

You may also start an advanced similarity search for this article.