USE OF FAT GRAFTING FOR THE TREATMENT OF COMPLEX WOUND: CASE REPORT
DOI:
https://doi.org/10.63845/ym6tbp49Keywords:
Fat, Wound healing, Autologous transplantationAbstract
O enxerto de gordura autóloga é uma opção terapêutica emergente para feridas que não estão prontas para enxerto de pele. O potencial regenerativo da gordura autóloga está nas células-tronco derivadas do tecido adiposo contidas na fração vascular estromal, que são capazes de se diferenciar em múltiplas linhagens celulares. No entanto, até o momento, não houve uma avaliação abrangente de sua eficácia em feridas complicadas agudas.¹ Este estudo tem como objetivo relatar um caso de ferida complexa localizada na região dorsal interescapular, secundária a ressecção oncológica de sarcoma, que foi satisfatoriamente tratada com o enxerto autólogo de gordura.
References
Saeed K, Khan FA, Qudus SBA, Javed S. Autologous Fat Grafting - A Step Forward in Wound Management. Int J Low Extrem Wounds. 2022 Dec;21(4):647-50. doi: 10.1177/15347346211073388. Epub 2022 Jan 12. PMID: 35018850. DOI: https://doi.org/10.1177/15347346211073388
Neuber, F. (1893) Fettransplantation Bericht uber die Verhandlungen der Deutscht Gesellsch Chir. Zentralblatt fur Chirurgie, 22, 66.
Vyas, Krishna SMD, Ph.D., MHS; Vasconez, Henry CMD; Morrison, Shane MD, MS; Mogni, Benjamin MD; Linton, Samuel MD; Hockensmith, Lindsay MD; Kabir, Tanvir MD; Zielins, Elizabeth MD; Najor, Anna BS; Bakri, Karim MD; Mardini, Samir MD. Fat Graft Enrichment Strategies: A Systematic Review. Plastic and Reconstructive Surgery 145(3):p 827-41, março de 2020. | DOI: 10.1097/PRS.0000000000006557 DOI: https://doi.org/10.1097/PRS.0000000000006557
Bertozzi N, Simonacci F, Grieco MP, Grignaffini E, Raposio E. The biological and clinical basis for the use of adipose-derived stem cells in the field of wound healing. Ann Med Surg. 2017;20:41-8. doi: 10.1016/j.amsu.2017.06.058. DOI: https://doi.org/10.1016/j.amsu.2017.06.058
Zhu M, Zhou Z, Chen Y, Schreiber R, Ransom JT, Fraser JK, et al. Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention. Ann Plast Surg 2010;64(2):222-8. [DOI] [PubMed] DOI: https://doi.org/10.1097/SAP.0b013e31819ae05c
Bellini E, Grieco MP, Raposio E. The science behind autologous fat grafting. Ann Med Surg. 2017;24:65–73. doi: 10.1016/j.amsu.2017.11.001. DOI: https://doi.org/10.1016/j.amsu.2017.11.001
Coleman SR. Enxertos de gordura estrutural: o preenchimento ideal. Clin Plast Surg. 2001;28:
-9.
Prakash O, Ali SS, Yaseen M, Sudhy IK, Venkateshwar PK, Kishore YR. Utility of Fat Grafting in Chronic Wounds. Indian J Plast Surg. 2024 May 30;57(3):201-7. doi: 10.1055/s-0044-1787174. PMID: 39139688; PMCID: PMC11319018.
Bellini E, Grieco M P, Raposio E. The science behind autologous fat grafting. Ann Med Surg (Lond) 2017;24(24):65–73. doi: 10.1016/j.amsu.2017.11.001.Indian J Plast Surg. 2024 May 30;57(3):201-7. doi: 10.1055/s-0044-1787174. PMID: 39139688; PMCID: PMC11319018. DOI: https://doi.org/10.1055/s-0044-1787174
Naderi N, Combellack E J, Griffin M et al. The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery. Int Wound J. 2017;14(01):112–24. doi: 10.1111/iwj.12569 DOI: https://doi.org/10.1111/iwj.12569
Cheng L, Han XF, Zhang C, Lv LL, Li FC. Occurrence of breast mucinous carcinoma after autologous fat grating for breast augmentation. Aesthetic Plast Surg. 2016 Fev;40(1):102-5. DOI: https://doi.org/10.1007/s00266-015-0605-6
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