BIA-ALCL AND DIFFERENTIAL DIAGNOSIS WITH PRIMARY SYSTEMIC ANAPLASTIC LARGE CELL LYMPHOMA: CASE REPORT

Authors

  • Rafaela Aline Gheller Faculdade de Medicina de Ribeirão Preto
  • Pedro Soler Coltro HCFMUSP RP/ Faculdade de Medicina de Ribeirão Preto
  • Marcelo Felix Da Silva HCFMUSP RP/ Faculdade de Medicina de Ribeirão Preto
  • Henrique Ovídio Coraspe Gonçalves Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brasil
  • Jayme Adriano Farina Junior HSL-PUCRS/Faculdade de Medicina de Ribeirão Preto

Keywords:

Breast implant, Anaplastic large-cell limphoma, Breast câncer

Abstract

This article reports a case of a patient who underwent breast augmentation in 2016 who evolved after 4 years with symptoms of adenomegaly of the supraclavicular, axillary and left cervical chains, as well as phlogosis in the ipsilateral breast. The case reported and publications raised bring to light the discussion of a case whose main diagnostic hypothesis was BIA-ALCL. She had a previous history of breast augmentation with placement of microtextured implants, in addition to clinical findings, physical examination, affected lymph node chains and imaging tests with compatible images in the CTR of the left breast.The markers obtained through the biopsy with immunohistochemistry of lymph node tissue were CD30 positive (strong and diffuse) and ALK negative, compatible with the diagnosis of BIA-ALCL.However, the atypical outcome obtained with the uncharacteristic findings of the surgical specimen after implant removal and bilateral total capsulectomy will be the focus of our case report.

Author Biographies

  • Rafaela Aline Gheller, Faculdade de Medicina de Ribeirão Preto

    Residente de Cirurgia Plástica , Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto,São Paulo, Brasil

  • Pedro Soler Coltro, HCFMUSP RP/ Faculdade de Medicina de Ribeirão Preto

    Preceptor da Divisão de Cirurgia Plástica do HCFMUSP RP, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brasil

  • Henrique Ovídio Coraspe Gonçalves, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brasil

    Cirurgião Plástico em Ribeirão Preto, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brasil

  • Jayme Adriano Farina Junior, HSL-PUCRS/Faculdade de Medicina de Ribeirão Preto

    Cirurgião Plástico Docente da divisão de Cirurgia Plástica do HCFMUSP RP, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brasil

References

Jaffe ES, Ashar BS, Clemens MW, et al. Best Practices Guideline for the Pathologic Diagnosis of Breast Implant-Associated Anaplastic Large-Cell Lymphoma. J Clin Oncol 2020; 38:1102.

Adrada BE, Miranda RN, Rauch GM, et al. Breast implant-associated anaplastic large cell lymphoma: sensitivity, specificity, and findings of imaging studies in 44 patients. Breast Cancer Res Treat 2014; 147:1.

Acevedo-Báñez I, García-Gomez FJ, Jiménez-Granero P, et al. 18F-FDG-PET/CT in implant-associated anaplastic large cell lymphoma of the breast. Br J Haematol 2015; 169:1.

Clemens MW, Miranda RN. Commentary on: CD30+ T Cells in Late Seroma May Not Be Diagnostic of Breast Implant-Associated Anaplastic Large Cell Lymphoma. Aesthet Surg J 2017.

Clemens MW, Miranda RN. Commentary on: Lymphomas Associated With Breast Implants: A Review of the Literature. Aesthet Surg J 2015; 35:545.

Mulligan C, Salisbury E, Tschuchnigg M, et al. ALK1-Negative Anaplastic Large Cell Lymphoma of the Breast from a Nonprosthesis Cyst. Plast Reconstr Surg Glob Open 2014; 2:e238.

Sathyanarayanan V, Lokesh KN, Lakshmaiah KC, et al. Anaplastic lymphoma kinase (ALK) positive anaplastic large cell lymphoma (ALCL) of breast in a patient without a breast implant. Ann Saudi Med 2014; 34:551.)

Published

2022-04-28

How to Cite

BIA-ALCL AND DIFFERENTIAL DIAGNOSIS WITH PRIMARY SYSTEMIC ANAPLASTIC LARGE CELL LYMPHOMA: CASE REPORT. (2022). Arquivos Catarinenses De Medicina, 51(1), 13-21. https://revista.acm.org.br/arquivos/article/view/1176

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