SEBACEOUS CARCINOMA: A MULTIDISCIPLINARY PATHOLOGY
Keywords:
Sebaceous carcinoma, Sebaceous glands, Muir-Torre syndromeAbstract
Carcinoma sebaceous is a malignant, aggressive and rare tumor, originating from the epithelium of the sebaceous glands, most commonly located in the head and neck. It is more common in women, in elderly patients, and can simulate ophthalmological pathologies. Its etiology is not well defined, can be presenting association with Muir-Torre syndrome, an autosomal dominant disease, in which sebaceous carcinoma is associated with visceral cancer, most often gastrointestinal tumors. The objective of this study is to report the case of a patient with a vegetating lesion in the left lower eyelid, whose diagnosis was conclusive for sebaceous carcinoma. Therefore, an active search for visceral neoplasms was carried out, establishing the diagnosis of sigmoid tumor.
References
Nelson BR, Hamlet KR, Gillard M, et al. Sebaceous carcinoma. J Am Acad Dermatol. 1995; 33:1-15.
Veras DO, Gumiero MPLD, Baptista MNM, et al. Reconstrução total de pálpebra superior no tratamento do carcinoma de glândula sebácea. Rev. Brasileira de Oftalmologia. 2020.
Alves S, Silva F, Ferreira M, et al. Atypical ‘benign behaviour’ of eyelid sebaceous carcinoma. BMJ Case Reports. 2012.
Park SK, Park J, Kim HU, et al. Sebaceous carcinoma: clinicopathologic analysis of 29 cases in a Tertiary Hospital in Korea. J Korean Med Sci. 2017;32(8):1351-9.
Tchornobay AM, Lévigne V, Favre J, et al. Extraocular sebaceous carcinoma. Acta Derm Venereol (Stockh). 1992;72:20-1.
Wick MR, Goellner JR, Wolfe JT, et al. Adnexal carcinomas of the skin II. Extraocular sebaceous carcinomas. Cancer. 1985;56:1163-72.
Paschal BR, Bagley CS. Sebaceous gland carcinoma of eyelid: complete response to sequential combination chemotherapy. N C Med J. 1985;46:473-4.
Aktar S, Oza KK, khan SA, et al. Muir-Torre Syndrome: Case report of a patient with concurrent jejunal and ureteral cancer and review of the literature. J Am Acad Dermatol. 1999;41:681-6.
Cieza-Dias DE, Martinez NC, Ortiz B, et al. Extraocular Sebaceous Carcinoma: A Report of 2 Cases. Actas Dermosifiliogr. 2012; 103:919-22.
Santos BMRS, Conceição AS, Fontes Daniel, et al. Síndrome de Muir-Torre: relato de caso. Rev Bras Coloproct, 2002;22(4): 260-3.
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