CHILDREN OSTEOPETROSIS AND MANDIBULAR RECONSTRUCTION WITH BIPHASIC CALCIUM PHOSPHATE CERAMICS – CASE REPORT
Keywords:
Osteopetrosis, Mandible, Reconstruction.Abstract
Osteopetrosis is a rare, recessive genetic transmission disease, in which is determined a poor osteoclastic activity. Osseous deposition is not remodeled, leading to abnormal and poor vascularized
tissue formation. There are other hematologic systemic manifestations due to compensatory extramedullary hematopoiesis, not on the scope of this case report. We related the case of a child with osteopetrosis and the sequential history of mandibular osseous cists, abscesses, osteomyelitis, serial osseous sequestrectomies, and prolonged antibiotic therapy, unsuccessfully partial mandibular reconstruction with plate exposition. We then planned a mandibular reconstruction with a prototyped mandibula in osseous ceramic, debridement of scared and fibrotic soft tissue, and a pectoral muscle cutaneous flap to local soft tissue coverture. In 3 years of post-operatory follow-up, no complications
were computed.
References
Dunphy L, Warfield A, Williams R. Osteomyelitis of the mandible secondary to malignant infantile osteopetrosis in an adult. BMJ Case Reports. 2019 Mar 1;12(3).
Nilesh K. Extensive maxillary osteomyelitis following tooth extraction in a patient with
osteopetrosis. BMJ Case Rep. 2020 Jun 7;13(6).
Allal S, Rabuel V, Gengler C, Douchet C, Allal F, Zwetyenga N. Case report of osteomyelitis of the mandible in osteopetrosis and management considerations. International Journal of Surgery Case Reports. 2021 Apr 1;81.
Satomura K, Kon M, Tokuyama R, Tomonari M, Takechi M, Yuasa T, et al. Osteopetrosis
complicated by osteomyelitis of the mandible: a case report including characterization of the
osteopetrotic bone. International Journal of Oral and Maxillofacial Surgery. 2007 Jan;36(1):86–93.
Eppley BL, Iii JJC. Technical Strategies Free Fibular Flap Reconstruction in Mandibular
Osteopetrosis.
Christodoulou EF, Nistikoulis G, Deftereos SP, Resident R. Maedica-a Journal of Clinical Medicine
Case report Case report MAEDICA-a Journal of Clinical Medicine Button Sequestrum Sign Due to Osteomyelitis of the Mandible Secondary to Malignant Infantile Osteopetrosis. Maedica A Journal of Clinical Medicine [Internet]. 16(3):2021. Available from:
https://doi.org/10.26574/maedica.2021.16.3.531
Trivellato AE, Ribeiro MC, Sverzut CE, Bonucci E, Nanci A, de Oliveira PT. Osteopetrosis
complicated by osteomyelitis of the maxilla and mandible: Light and electron microscopic findings. Head and Neck Pathology. 2009 Dec;3(4):320–6.
Bouler JM, Pilet P, Gauthier O, Verron E. Biphasic calcium phosphate ceramics for bone
reconstruction: A review of biological response. Vol. 53, Acta Biomaterialia. Acta Materialia Inc; 2017. p. 1–12.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Arquivos Catarinenses de Medicina
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
