FATORES ASSOCIADOS AO CONTROLE GLICÊMICO EM PACIENTES PORTADORES DE DIABETES MELLITUS TIPO 1

Authors

  • Patricia R Guzatti Universidade do Sul de Santa Catarina
  • Amely PS Balthazar Universidade do Sul de Santa Catarina
  • Maria Heloisa BS Canalli Universidade do Sul de Santa Catarina
  • Thais F Machado Universidade do Sul de Santa Catarina

Keywords:

Diabetes Mellitus tipo 1. Hemoglobina A glicosilada. Insulina. Atividade motora. Complicações do diabetes.

Abstract

Objetivo: Identificar fatores associados ao controle glicêmico em diabéticos tipo 1. Métodos: Estudo transversal analítico realizado no Hospital Governador Celso Ramos, com 48 prontuários. Avaliou-se controle glicêmico conforme fatores sociodemográficos, de hábitos de vida e relacionados ao tratamento, conforme a Diretriz da Sociedade Brasileira de Diabetes 2013-2014. Realizaram-se análises descritiva e bivariada pelo teste exato de Fisher, com nível de significância de 95% (p?0,05). Aprovado no CEP UNISUL e HGCR. Resultados: Predomínio de homens (54,17%), com menos de 25 anos de idade (56,25%) e mais de dez anos de doença (52,08%). A média geral de HbA1c foi 8,68% (± 2,17); valores ?7% foram obtidos em 22,92% da população. Dentre os pacientes com controle glicêmico adequado, 90,91% residiam na Grande Florianópolis, 60% praticavam atividade física, 63,64% usavam análogos de insulina, 90,91% monitoravam a glicemia capilar três ou mais vezes/dia e 100% aplicaram insulina três ou mais vezes/dia. Dos pacientes com HbA1c ? 7%, 100% não apresentavam complicações crônicas. Conclusão: Praticar atividade física, realizar terapia insulínica intensiva, utilizar análogos e morar na Grande Florianópolis foram os principais fatores contribuintes com o adequado controle glicêmico.

References

Lipton RB, Drum M, Burnet D, Rich B, Cooper A, Baumann E, Hagopian W, et al. Obesity at the onset of diabetes in an ethnically diverse population of children: what does it mean for epidemiologists and clinicians? Pediatrics. 2005; e553-60.

Negrato CA, Dias JPL, Teixeira MF, Dias A, Salgado MH, Lauris JR, et al. Temporal trends in incidence of Type1 diabetes between 1986 and 2006 in Brazil. Journal of Endocrinological Investigation. 2010; 33(6):373-7.

The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993; 329(14):977-86.

Diretrizes da Sociedade Brasileira de Diabetes. São Paulo: AC Farmacêutica; 2013-2014

Gomes MB, Coral M, Cobas RA, Dib SA, Canani LH, Nery M, et al. Prevalence of adults with type 1 diabetes who meet the goals of care in daily clinical practice: A Nationwide multicenter study in Brasil. Diabetes Research and clinical practice. 2012; 97:63-70.

Vilar L. Endocrinologia Clínica. 5. ed. Rio de Janeiro: Guanabara Koogan; 2013. p.790-1.

Marques RMB, Fornés NS, Stringhini MLF. Fatores socioeconômicos, demográficos, nutricionais e de atividade física no controle glicêmico de adolescentes portadores de diabetes melito tipo 1. Arq Bras Endocrinol Metab. 2011; 55(3):194-202.

Rodrigues TC, Pecis M, Canani LH, Schreiner L, Kramer CK, Bivatti K, et al. Caracterização de Pacientes com Diabetes Mellitus tipo 1 do Sul do Brasil: complicações crônicas e fatores associados. Rev Assoc Bras. 2010; 56(1):67-73.

Mendes ANV, Fittipaldi JAS, Neves RCS, Chacra AR, Moreira ED Jr. Acta Diabetol. 2010; 47:137-45.

Liberatore Jr RDR, Demartini AAC, Ono AHA, Andrade GC. Prevalência de obesidade em crianças e adolescente com diabetes melito tipo 1. Rev Paul Pediatr. 2008; 26(2):142-5.

Paulino MFVM, Marini SHL, Guerra Jr D, Morcillo AM. Crescimento e composição corporal de uma coorte de crianças e adolescentes com diabetes tipo 1. Arq Bras Endocrinol Metab. 2013; 57(8):623-31.

Dabelea D, Mayer-Davis EJ, Saydah S, Imperatore G, Linder B, Divers J, et al. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. JAMA. 2014; 311(17):1778-86.

Jose LP, Cardoso-Demartini AA, Liberatore RD Jr., Paulino MF, de Lemos-Marini SH, Guerra G Jr., et al. Clinical and laboratory profile of pediatric and adolescent patients with type 1 diabetes. J Pediatr. 2009; 85(6):490-4.

Rosilio M, Cotton JB, Wieliczko MC, Gendrault B, Carel JC, Couvaras O, et al. Factors Associated With Glycemic Control. Diabetes Care. 1998; 21(7):1146-53.

Forga A, Gõni MJ, Cambra K, Ibàñez B, Mozas D, Checa M. Influence of age at diagnosis on glycaemic control evolution in patients with type 1 diabetes. Diabetes & Metabolism. 2013; 39:519-23

Gomes MB, Castro SH, Garfinkel T, Fernandes LMP, Cunha EF, Lobão VI. J Pediatr. 2001; 77(1):41-4.

Al-Odayani AN, Alsharqi OZ, Ahmad AMK, Al Asmari AK, Al-Borie HM, Qattan AMN. Children’s Glycemmic Control: Mother’s Knowledge and Socioeconomic Status. Global Journal of Health Science. 2013; 5(6):214-26.

Benevento D, Bizzarri C, Pitocco D, Crino A, Moretti C, Spera S, et al. Computer use, free time activities and metabolic control in patients with type 1 diabetes. Diabetes Research and Clinical Practice. 2010;80:e32-4.

Queiroz KC, Silva IN, Alfenas RCG. Associação entre fatores nutricionais e o controle glicêmico de crianças e adolescentes com diabetes melito tipo 1. Arq Bras Endocrinol Metab. 2010; 54(3):319-25.

Galler A, Lindau M, Ernert A, Thalemann R, Raile K. Associations between media consumption habits, physical activity, socioeconomic status, and glycemic control in children, adolescentes, and young adults with type 1 diabetes. Diabetes Care. 2011; 34:2356-59.

Souto DL, Miranda MP. Physical excercises on glycemic control in type 1 diabetes mellitus. Nutr Hosp. 2011;26:425-29.

Kennedy A, Nirantharakumar K, Chimen M, Pang TT, Hemming K, Andrews RC, et al. Does Exercise Improve Glycaemic Control in Type 1 Diabetes? A Systematic Reviewand Meta-Analysus. 2013; 8(3):e58861.

Carral F, Gutiérrez JV, Ayala MC, Carcía G, Aguilar M. Intense physical activity is associated with better metabolic control in patients with type 1 diabetes. Diabetes Research and Clinical Practice. 2013; 1001:45-9.

Honkasalo MT, Elonheimo OM, Sane T. Severe hypoglycaemia in drug-treated diabetic patients needs attention: A population-based study. Scandin Journ PrimHeal Care. 2011; 29:165-70.

Cherubini V, Pintaudi B, Rossi MC, Lucisano G, Pellegrini F, Chiumello G, et al. Severe hypoglycemia and ketoacidosis over oneyear in Italian pediatric population with type 1 diabetes mellitus: A multicenter retrospective observational study. Nutrition, Metabolism & Cardiovascular Disease. 2014; 24:538-46.

Sociedade Brasileira de Diabetes. Posicionamento oficial SBD n. 1/2012. Diagnóstico e tratamento do Diabetes tipo 1. 2012 Nov.

Vardi M, Jacobson E, Nini A, Bitterman H. Intermediate acting versus long acting insulin for type 1 diabetes mellitus. Cochrane Database of Systematic Reviews. 2008, Issue 3. Art. n.: CD006297.

Agência Nacional de Vigilância Sanitária (ANVISA). Insulina Glargina e Insulina Detemir no Controle da Diabetes Mellitus Tipo 1. Boletim Brasileiro de Avaliação de Tecnologias em Saúde (BRATS) [Internet]. 2010 Dez; V(13):412; [acesso em 2014 Set. 21]. Disponível em: http://bvsms.saude.gov.br/bvs/ct/pdf/brats2010_n13.pdf.

Sanches ACC, Correr CJ, Venson Rafael, Pontarolo R. Revisiting the efficacy of long-acting insulin analogues on adults with type 1 diabetes using mixed-treatment comparisons. Diabetes Research and Clinical Practice. 2011; 94:333-9.

Tricco AC, Ashoor HM, Antony J, Beyene J, Veroniki AA, Isaranuwatchai W, et al. Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic reviewand network meta-analysis. BMJ. 2014; 349:g5459.

Rys P, Pankiewicz O, Lach K, Kwaskowski A, Baran LS, Malecki MT. Efficacy and safety comparison of rapid-acting insulin aspart and regular human insulin in thetreatment of type 1 and type 2 diabetes mellitus: A systematic review. Diabetes & Metabolism. 2011; 37:190-200.

Lecomte P, Romon I, Fosse S, Simon D, Campagna FA. Self-monitoring of blood glucose in people with type 1 and type 1 diabetes living in France: The Entred study 2001. Diabetes & Metabolism. 2008; 34:219-26.

Skeie S, Kristensen GBB, Carlsen S, Sandberg S. Self-Monitoring of Blood Glucose in Type 1 Diabetes Patients with Insufficient Metabolic Control: Focused Self-Monitoring of Blood Glucose Intervention Can Lower Glycated Hemoglobin AIC. Journal of Diabetes Science and Technology. 2009; 3(1):83-8.

Souto DL, Zajdenverg L, Rodacki M, Rosado EL. Impact of advanced and basic carbohydrate counting methods on metabolic control in patients with type 1 diabetes. Nutrition. 2014; 30:286-90.

Spiegel G, Bortsov A, Bishop FK, Owen D, Klingensmith GJ, Davis ELJ, et al. Randomized Nutrition Education Intervention to Improve Carbohydrate Count in Adolescents with Type 1 Diabetes Study: Is More Intensive Education Needed? Journal of the Academy of Nutritionand Dietetics. 2012; 112:1736-46.

Reichard P, Nilsson BY, Rosenqvist U. The effectof long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus. N Engl J Med. 1993; 329(5):304.

Vardi M, Jacobson E, Nini A, Bitterman H. Intermediateacting versus long acting insulin for type 1 diabetes mellitus. Cochrane Database of Systematic Reviews. 2008, Issue 3. Art. n.: CD00629.

Published

2017-07-11

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How to Cite

FATORES ASSOCIADOS AO CONTROLE GLICÊMICO EM PACIENTES PORTADORES DE DIABETES MELLITUS TIPO 1. (2017). Arquivos Catarinenses De Medicina, 46(2), 26-38. https://revista.acm.org.br/arquivos/article/view/266

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