ESCLEROSE SISTÊMICA COM AGRAVAMENTO POR FENÔMENO DE RAYNAUD SECUNDÁRIO: RELATO DE CASO
Keywords:
Esclerose Sistêmica. Fenômeno de Raynaud. Autoimune. Micro Lesão vascular. Amputações.Abstract
Apresentamos um caso de paciente feminino de 49 anos, que apresentou se ao consultório relatando palidez e cianose, associados a prurido em partes distais dos quirodáctilos com evolução subsequente para necrose e remoção cirúrgica. Após anamnese detalhada e exames complementares, chegou-se ao diagnóstico definitivo de esclerose sistêmica. Ainda no caso em questão, paciente possui agravamento do quadro clínico em decorrência do fenômeno de Raynaud secundário, o que acarretou diversas remoções cirúrgicas de membros como quirodáctilo, pododáctilo e membro inferior esquerdo, em decorrência dos ataques de isquemia periférica.References
Gabrielli A, Avvedimento EV, Krieg T. Scleroderma. N Engl J Med. 2009;360:1989–2003.
Watad A, Rosenberg V, Tiosano S, et al. Silicone breast implants and the risk of autoimmune/rheumatic disorders: a real-world analysis. Int J Epidemiol. 2018;47:1846–1854.
Johnson SR, Soowamber ML, Fransen J, et al. There is a need for new systemic sclerosis subset criteria. A content analytic approach. Scand J Rheumatol. 2018;47(1):62-70.
Altorok N, Almeshal N, Wang Y, Kahaleh B. Epigenetics, the holy grail in the pathogenesis of systemic sclerosis. Rheumatology. 2015;54(10):1759–1770.
Mayes MD. Scleroderma epidemiology. Rheum Dis Clin North Am. 2003;29(2):239-254.
Hughes, M., & Herrick, A. L. Systemic sclerosis. British Journal of Hospital Medicine. 2019;80(9), 530-536.
Cutolo M, Smith V, Furst DE, et al. Points to consider-Raynaud’s phenomenon in systemic sclerosis. Rheumatology (Oxford). 2017;56(suppl_5):v45–v48
Wigley FM, Flavahan NA. Raynaud’s Phenomenon. N Engl J Med. 2016;375:556–565.
Hughes M, Moore T, O’Leary N et al. A study comparing videocapillaroscopy and dermoscopy in the assessment of nailfold capillaries in patients with systemic sclerosis–spectrum disorders. Rheumatology. 2015;54(8):1435–1442.
Cutolo, M., Soldano, S., & Smith, V. Pathophysiology of systemic sclerosis: current understanding and new insights. Expert review of clinical immunology. 2019;15(7), 753-764.
Hughes M, Herrick AL. Digital ulcers in systemic sclerosis. Rheumatology. 2017;56(1):14–25.
Man A, Zhu Y, Zhang Y et al. The risk of cardiovascular disease in systemic sclerosis: a population-based cohort study. Ann Rheum Dis. 2013;72(7):1188–1193.
Van Den Hoogen, F, et al. "2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative." Arthritis & Rheumatism. 2013; 65.11: 2737-2747.
Iwamoto N, Distler O. Molecular targets for therapy in systemic sclerosis. Fibrogenesis Tissue Repair. 2012;5(Suppl 1):S19.
Bruni C, Cuomo G, Rossi FW, Praino E, Bellando-Randone S. Kidney involvement in systemic sclerosis: from pathogenesis to treatment. J Scleroderma Relat Disord. 2018;3(1):43–52.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Arquivos Catarinenses de Medicina
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.