THE AMNIOTIC MEMBRANE AS AN ALTERNATIVE DRESSING: NEW REGULATORY ADVANCES
Keywords:
Burn, Biological dressings, Amniotic membraneAbstract
Introduction: Brazil is the only country in South America that does not have regulations for the
distribution of amniotic membrane (AM) for clinical use. This tissue is widely accepted as an
alternative biological dressing in major burns and in other fields of medicine. Methods:
communication reports between the Skin Bank of Porto Alegre and the health authorities, technical
notes and the current regulations that involve the procedures for the clinical use of the amniotic
membrane were reviewed. Results: like all human tissue, the donation of MA is legally permitted, in
light of the Transplantation Law. Last year, according to opinion No 12/2021, the CFM stated
thatthere was scientific support for its clinical use, on a non-experimental basis. At the moment, the
liberation of AM use is awaiting approval by the SNT and CONITEC. Conclusion: regulation of the
amniotic membrane could provide an adequate, low-cost and highly available biological dressing.
References
Pretto AS, Pretto L, Souza AFD, Chem EM, Ely PB, Bonamigo RR. Allogeneic skin donors from a tissue bank in Southern Brazil: clinical and epidemiological profiles and microbial colonization of skin. Int J Dermatol. 2019 Mar;58(3):325-332. doi: 10.1111/ijd.14254. Epub 2018 Sep 23. PMID: 30246340.
Ribeiro SG, Zanatelli C, Schorer B, Chem EM. Banco de Tecidos Humanos - Relatório Descritivo do Segmento Pele. Porto Alegre (RS): Banco de Pele Dr. Roberto Corrêa Chem/ICSMPA. 2022.
Ribeiro SG, Zanatelli C, Schorer B, Chem EM. Relatório Descritivo das Tramitações da Membrana Amniótica. Porto Alegre (RS): Banco de Pele Dr. Roberto Corrêa Chem/ICSMPA. 2022.
Koob, T J., Rennert, R., Zabek, N., Massee, M., Lim, J. J., Temenoff, J. S., … Gurtner, G. Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing. International Wound Journal. 2013; 10(5), 493–500. doi:10.1111/iwj.12140
Mohammadi AA, Johari HG, Eskandari S. Effect of amniotic membrane on graft take in extremity burns. Burns. 2013;39(6):1137‐1141.
Mohammadi AA, Riazi H, Hasheminasab MJ, Sabet B, Mohammadi MK, Abbasi S, et al. Amniotic membrane dressing vs conventional topical antibiotic dressing in hospitalized burn patients. IRCMJ 2009;11(1):66–70
Branski LK, Herndon DN, Celis MM, Norbury WB, Masters OE, Jeschke MG. Amnion in the treatment of pediatric partial-thickness facial burns. Burns. 2008;34:393–9
Kogan S, Sood A, Granick MS. Amniotic Membrane Adjuncts and Clinical Applications in Wound Healing: A Review of the Literature. Wounds. 2018 Jun;30(6):168-173. PMID: 30059334.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Arquivos Catarinenses de Medicina
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
