CASCA E POLPA DE PASSIFLORA NA SÍNDROME METABÓLICA: UMA REVISÃO SISTEMÁTICA DE ENSAIOS CLÍNICOS RANDOMIZADOS
Keywords:
Maracujá. Resistência à Insulina. Saúde do Adulto.Abstract
A síndrome metabólica (SM) caracteriza-se como um conjunto de distúrbios cardiometabólicos, que engloba alterações cardiometabólicas relacionadas diretamente a hereditariedade e ao estilo de vida. Sem tratamento especifico, porém sua terapêutica visa atenuar o risco de maiores complicações, através de estratégias comportamentais e, eventualmente, medicamentosas. Dietas ricas em alimentos in natura, melhoram o perfil lipidêmico, glicemia, níveis pressóricos e o estresse oxidativo, provendo benefícios à saúde. Frente a esta descobertas, estudiosos se debruçado no estudo de produtos naturais. Passiflora ssp. destaca-se por suas propriedades terapêuticas, devido aos compostos bioativos. Este estudo tem como objetivo identificar a utilização de Passiflora ssp. na atenuação dos componentes da SM. Trata-se de uma revisão sistemática, seguindo as diretrizes PRISMA, nas bases de dados/plataformas eletrônicas: PubMed Central, Scopus e Web of Science™, até abril de 2023. Para avaliar o risco de viés, foi utilizado a ferramenta Cochran Risk of Bias 2.0. Foram incluídos 8 ensaios clínicos randomizados, 50% investigaram a casca e 50% a polpa de Passiflora. Ambos evidenciaram efeitos anti-glicemiantes, antidislipidêmicos e anti-hipertensivos. Não houve impacto na composição corporal. Conclui-se que a utilização de Passiflora ssp. é seguro, atenuando inflamação, parâmetros glicídicos, insulinêmicos, dislipidêmicos e pressóricos, sugerindo ser uma terapia alternativa para a SM.
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